Textbook Question
Explain why it would be difficult for a mature multinucleate cell such as a skeletal muscle fiber to divide by mitosis.
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Ch. 4 Histology
Amerman2nd EditionHuman Anatomy & PhysiologyISBN: 9780136873822
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Table of contents
- Ch. 1 Introduction to Anatomy and Physiology26
- Ch. 2 The Chemistry of Life38
- Ch. 3 The Cell55
- Ch. 4 Histology47
- Ch. 5 The Integumentary System30
- Ch. 6 Bones and Bone Tissue36
- Ch. 7 The Skeletal System40
- Ch. 8 Articulations19
- Ch. 9 The Muscular System36
- Ch. 10 Muscle Tissue and Physiology29
- Ch. 11 Introduction to the Nervous System and Nervous Tissue28
- Ch. 12 The Central Nervous System42
- Ch. 13 The Peripheral Nervous System41
- Ch. 14 The Autonomic Nervous System and Homeostasis31
- Ch. 15 The Special Senses39
- Ch. 16 The Endocrine System42
- Ch. 17 The Cardiovascular System I: The Heart30
- Ch. 18 The Cardiovascular System II: The Blood Vessels43
- Ch. 19 Blood32
- Ch. 20 The Lymphatic System and Immunity45
- Ch. 21 The Respiratory System27
- Ch. 22 The Digestive System27
- Ch. 23 Metabolism and Nutrition7
- Ch. 24 The Urinary System39
- Ch. 25 Fluid, Electrolyte, and Acid-Base Homeostasis39
- Ch. 26 The Reproductive System10
- Ch. 27 Development and Heredity5
Chapter 4, Problem 3a
Describe the roles of the following components of the ECM:
Collagen fibers
Verified step by step guidance1
Collagen fibers are a major structural component of the extracellular matrix (ECM) and provide tensile strength to tissues, helping them resist stretching forces.
These fibers are composed of collagen proteins, which are organized into a triple-helix structure, making them strong and durable.
Collagen fibers are particularly abundant in connective tissues such as tendons, ligaments, and the dermis of the skin, where they maintain structural integrity and support.
In addition to providing mechanical strength, collagen fibers also play a role in cell adhesion, migration, and tissue repair by interacting with other ECM components and cell surface receptors.
Collagen fibers are synthesized by fibroblasts and other specialized cells, and their production and organization are critical for maintaining normal tissue function and healing after injury.
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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Extracellular Matrix (ECM)
The extracellular matrix (ECM) is a complex network of proteins and carbohydrates that provides structural and biochemical support to surrounding cells. It plays a crucial role in tissue and organ function, influencing cell behavior, migration, and differentiation. The ECM is composed of various components, including collagen, elastin, glycoproteins, and proteoglycans, each contributing to the overall integrity and functionality of tissues.
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3:31
Bone Matrix
Collagen Fibers
Collagen fibers are the primary structural proteins found in the ECM, providing tensile strength and support to tissues. They are composed of collagen molecules that assemble into fibrils, which then form larger fibers. Collagen is essential for maintaining the structural integrity of various tissues, including skin, bone, cartilage, and tendons, and plays a vital role in wound healing and tissue repair.
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Tissue Function and Repair
The ECM, particularly through its collagen fibers, is integral to tissue function and repair. Collagen not only supports the physical structure of tissues but also interacts with cells to regulate their behavior during processes such as growth, healing, and inflammation. Understanding the role of collagen in the ECM is essential for comprehending how tissues respond to injury and maintain homeostasis.
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Related Practice
Textbook Question
Imagine that a disease turns the simple epithelia of the lungs, kidney tubules, and intestines into keratinized stratified squamous epithelia. What effect would this change in form have on the functions of these tissues?
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Textbook Question
Describe the roles of the following components of the ECM:
Proteoglycans
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Textbook Question
Describe the roles of the following components of the ECM:
Glycosaminoglycans
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Textbook Question
Describe the roles of the following components of the ECM:
Reticular fibers
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Textbook Question
In the disease scleroderma, excessive collagen, glycosaminoglycans, and glycoproteins are produced and deposited in tissues throughout the body. Predict the effects of this disease.
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