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Multiple Choice
Functionally, troponin provides a binding site for which ions?
A
Magnesium
B
Potassium
C
Calcium
D
Sodium
Verified step by step guidance
1
Understand the role of troponin in muscle contraction: Troponin is a regulatory protein complex found in skeletal and cardiac muscle fibers. It plays a critical role in the contraction process by interacting with calcium ions.
Recall the mechanism of muscle contraction: When a muscle fiber is stimulated, calcium ions are released from the sarcoplasmic reticulum into the cytoplasm. These ions bind to troponin, causing a conformational change.
Identify the specific ion that binds to troponin: Calcium ions (Ca²⁺) are the ones that bind to troponin, specifically to the troponin C subunit, initiating the contraction process.
Understand the result of calcium binding: When calcium binds to troponin, it causes a shift in the position of tropomyosin, exposing the binding sites on actin filaments for myosin heads, which leads to muscle contraction.
Review why other ions are not correct: Magnesium (Mg²⁺), Potassium (K⁺), and Sodium (Na⁺) have different roles in cellular processes, such as maintaining membrane potential or acting as cofactors, but they do not bind to troponin to initiate muscle contraction.