Understand that the epidermis is the outermost layer of the skin and consists of multiple layers, particularly in thick skin (e.g., palms and soles). These layers are organized from the deepest to the most superficial.
Recall the five layers of the epidermis in thick skin: Stratum basale (deepest), Stratum spinosum, Stratum granulosum, Stratum lucidum, and Stratum corneum (most superficial).
Note that the Stratum basale is the deepest layer, responsible for cell division and regeneration. It is followed by the Stratum spinosum, which provides strength and flexibility to the skin.
Next, the Stratum granulosum contains cells that begin to die and become keratinized. Above this is the Stratum lucidum, a clear layer found only in thick skin, providing an additional barrier.
Finally, the Stratum corneum is the outermost layer, consisting of dead, keratinized cells that protect the skin from external damage and water loss. Use this sequence to identify the correct answer from the options provided.