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Multiple Choice
What directly stimulates a skeletal muscle fiber to contract at the neuromuscular junction?
A
Binding of oxygen to myoglobin within the muscle fiber
B
Release of epinephrine from the adrenal medulla into the bloodstream
C
Secretion of calcium ions into the synaptic cleft from the muscle fiber
D
Release of acetylcholine from a motor neuron onto the muscle fiber motor end plate
Verified step by step guidance
1
Understand that the neuromuscular junction is the synapse or connection point between a motor neuron and a skeletal muscle fiber.
Recognize that muscle contraction is initiated by a chemical signal released from the motor neuron, which must cross the synaptic cleft to stimulate the muscle fiber.
Identify the neurotransmitter involved in this process, which is acetylcholine (ACh), released from the motor neuron into the synaptic cleft.
Know that acetylcholine binds to receptors on the motor end plate of the muscle fiber, causing ion channels to open and leading to depolarization of the muscle membrane.
This depolarization triggers an action potential in the muscle fiber, ultimately leading to muscle contraction.