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Multiple Choice
Which statement describes the mechanism of muscle contraction?
A
The myosin heads bind to actin filaments, forming cross-bridges and pulling the actin filaments toward the center of the sarcomere.
B
Calcium ions are released from the sarcoplasmic reticulum and bind to myosin, causing it to detach from actin.
C
The sarcomere lengthens as the actin and myosin filaments move apart, resulting in muscle contraction.
D
ATP is hydrolyzed to ADP and phosphate, which directly causes the actin filaments to slide past the myosin filaments.
Verified step by step guidance
1
Begin by understanding the structure of a sarcomere, the basic unit of a muscle fiber, which consists of actin and myosin filaments.
Recognize the role of calcium ions in muscle contraction. Calcium ions are released from the sarcoplasmic reticulum and bind to troponin, not myosin, which causes a conformational change that exposes binding sites on actin filaments.
Learn about the cross-bridge cycle: Myosin heads bind to the exposed sites on actin filaments, forming cross-bridges. This is a crucial step in muscle contraction.
Understand the role of ATP in muscle contraction. ATP binds to myosin, causing it to detach from actin. ATP is then hydrolyzed to ADP and inorganic phosphate, which provides energy for the myosin head to pivot and pull the actin filament toward the center of the sarcomere.
Conclude with the sliding filament theory: Muscle contraction occurs as actin filaments slide past myosin filaments, shortening the sarcomere and thus the muscle fiber.