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Multiple Choice
Which hormone promotes an increase in the activity of osteoclasts?
A
Glucagon
B
Insulin
C
Calcitonin
D
Parathyroid hormone (PTH)
Verified step by step guidance
1
Understand the role of osteoclasts: Osteoclasts are cells that break down bone tissue, a process known as bone resorption. This is important for the maintenance, repair, and remodeling of bones.
Identify the hormones involved in bone metabolism: The main hormones that regulate bone metabolism include parathyroid hormone (PTH), calcitonin, and vitamin D.
Examine the function of parathyroid hormone (PTH): PTH is secreted by the parathyroid glands and plays a crucial role in regulating calcium levels in the blood. It increases the activity of osteoclasts, leading to the release of calcium from bones into the bloodstream.
Contrast with calcitonin: Calcitonin, produced by the thyroid gland, has the opposite effect of PTH. It decreases osteoclast activity, promoting bone formation and reducing blood calcium levels.
Conclude the relationship: Since PTH increases osteoclast activity, it is the hormone that promotes an increase in the activity of osteoclasts, leading to higher calcium levels in the blood.