Table of contents

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System2h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

9. Muscle Tissue

Sliding Filament Theory and the Sacromere

Anatomy & Physiology

9. Muscle Tissue

Sliding Filament Theory and the Sacromere

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Multiple Choice

What causes the release of calcium ions into the sarcoplasm from the terminal cisterns during muscle contraction?

The depolarization of the T-tubules

The hydrolysis of ATP by myosin heads

The arrival of an action potential at the neuromuscular junction

The binding of acetylcholine to receptors on the sarcolemma

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Verified step by step guidance

Understand the structure of a muscle fiber: Muscle fibers contain structures called sarcoplasmic reticulum (SR) and T-tubules. The SR stores calcium ions, and T-tubules are invaginations of the sarcolemma that help transmit electrical signals.

Recognize the role of calcium ions: Calcium ions are crucial for muscle contraction as they bind to troponin, causing a conformational change that allows myosin to bind to actin, initiating contraction.

Identify the process of muscle contraction initiation: An action potential travels along a motor neuron to the neuromuscular junction, where it triggers the release of the neurotransmitter acetylcholine.

Examine the role of acetylcholine: Acetylcholine binds to receptors on the sarcolemma, leading to depolarization and the generation of an action potential that travels along the sarcolemma and down the T-tubules.

Connect depolarization to calcium release: The depolarization of the T-tubules triggers the opening of calcium channels in the terminal cisterns of the sarcoplasmic reticulum, releasing calcium ions into the sarcoplasm and facilitating muscle contraction.