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Multiple Choice
In the context of organ systems, a patient receiving IV acyclovir should be monitored for which adverse reaction?
A
Cardiotoxicity
B
Neurotoxicity
C
Hepatotoxicity
D
Nephrotoxicity
Verified step by step guidance
1
Understand the context: Acyclovir is an antiviral medication commonly used to treat infections caused by certain types of viruses. It is important to know how this drug is processed in the body and which organ systems it affects.
Identify the primary organ system involved: Acyclovir is primarily excreted by the kidneys. Therefore, the renal system is the main organ system involved in the elimination of this drug from the body.
Consider potential adverse reactions: Since acyclovir is excreted through the kidneys, it can potentially cause nephrotoxicity, which is toxicity in the kidneys. This is a known adverse effect of acyclovir, especially in patients with pre-existing kidney conditions or those receiving high doses.
Evaluate the other options: Cardiotoxicity refers to damage to the heart, neurotoxicity refers to damage to the nervous system, and hepatotoxicity refers to damage to the liver. These are not commonly associated with acyclovir.
Conclude the monitoring focus: Based on the pharmacokinetics of acyclovir and its known adverse effects, patients receiving IV acyclovir should be monitored for nephrotoxicity, making it the correct answer.