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Multiple Choice
Antibody-dependent cell-mediated cytotoxicity (ADCC) would be used to destroy which of the following?
A
Bacteria in the bloodstream
B
Red blood cells
C
Platelets
D
Virus-infected cells
Verified step by step guidance
1
Understand the concept of Antibody-dependent cell-mediated cytotoxicity (ADCC): ADCC is an immune response where antibodies bind to a target cell, such as a virus-infected cell, and recruit immune cells to destroy the target.
Identify the role of antibodies in ADCC: Antibodies recognize and bind to antigens on the surface of target cells, marking them for destruction by immune cells like natural killer (NK) cells.
Recognize the types of cells typically targeted by ADCC: ADCC is primarily involved in targeting and destroying cells that are infected by viruses or are otherwise abnormal, such as cancer cells.
Evaluate the options given: Consider which of the options (bacteria in the bloodstream, red blood cells, platelets, virus-infected cells) are typically targeted by ADCC.
Conclude that virus-infected cells are the correct target for ADCC: Virus-infected cells display viral antigens on their surface, which are recognized by antibodies, leading to their destruction by immune cells through the ADCC mechanism.