Step 1: Begin by understanding the hierarchical organization of skeletal muscle. Skeletal muscle is composed of multiple levels of structure, starting from the largest unit (the muscle itself) and progressing to the smallest unit (the myofilament). Each level is nested within the next.
Step 2: Define each component:
- Muscle: The largest structure, composed of bundles of fascicles.
- Fascicle: A bundle of muscle fibers surrounded by connective tissue.
- Muscle fiber: A single muscle cell, which contains many myofibrils.
- Myofibril: A cylindrical structure within the muscle fiber, made up of repeating units called sarcomeres.
- Myofilament: The smallest structure, composed of actin and myosin proteins that interact to produce muscle contraction.
Step 3: Arrange the components from largest to smallest based on their definitions: Muscle > Fascicle > Muscle Fiber > Myofibril > Myofilament.
Step 4: Compare the given options to the correct hierarchical order. Identify the option that matches the sequence Muscle > Fascicle > Muscle Fiber > Myofibril > Myofilament.
Step 5: Eliminate incorrect options by checking for any deviations from the correct order. Select the option that accurately reflects the hierarchy of skeletal muscle components.