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Multiple Choice
In which region of the nephron is a steep osmotic gradient created?
A
Proximal convoluted tubule
B
Distal convoluted tubule
C
Collecting duct
D
Loop of Henle
Verified step by step guidance
1
Understand the function of the nephron: The nephron is the functional unit of the kidney, responsible for filtering blood and forming urine. It consists of several regions, each with specific roles in the process of urine formation.
Identify the role of the Loop of Henle: The Loop of Henle is a U-shaped structure in the nephron that plays a crucial role in concentrating urine and creating an osmotic gradient in the kidney's medulla.
Explain the osmotic gradient: The osmotic gradient is a difference in solute concentration across a membrane. In the kidney, this gradient is essential for water reabsorption and urine concentration.
Describe the mechanism in the Loop of Henle: The descending limb of the Loop of Henle is permeable to water but not to solutes, allowing water to leave the filtrate and enter the surrounding medulla, increasing the filtrate's osmolarity. The ascending limb is impermeable to water but actively transports solutes out, decreasing the filtrate's osmolarity and contributing to the osmotic gradient.
Conclude why the Loop of Henle is the correct answer: The Loop of Henle's unique structure and function create a steep osmotic gradient in the kidney's medulla, which is essential for the kidney's ability to concentrate urine and conserve water.