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Multiple Choice
Which of the following is NOT a step used by cytotoxic T cells to kill infected host cells?
A
Secretion of granzymes to induce apoptosis in the target cell
B
Recognition of antigen presented by MHC class I molecules
C
Phagocytosis of the target cell
D
Release of perforin to create pores in the target cell membrane
Verified step by step guidance
1
Understand the role of cytotoxic T cells: Cytotoxic T cells are a type of immune cell that play a crucial role in the body's defense against infected or cancerous cells. They are part of the adaptive immune system and are specifically designed to target and destroy cells that display foreign antigens.
Identify the mechanism of action: Cytotoxic T cells kill infected host cells through a series of steps that involve recognition and destruction. They recognize infected cells by detecting antigens presented by MHC class I molecules on the surface of these cells.
Examine the process of apoptosis induction: Once the cytotoxic T cell recognizes the infected cell, it releases granzymes, which are serine proteases that enter the target cell and induce apoptosis, a programmed cell death process.
Explore the role of perforin: Cytotoxic T cells also release perforin, a protein that forms pores in the target cell's membrane. This pore formation facilitates the entry of granzymes into the target cell, leading to apoptosis.
Clarify the incorrect step: Phagocytosis is not a mechanism used by cytotoxic T cells to kill infected host cells. Phagocytosis is a process used by other immune cells, such as macrophages, to engulf and digest pathogens or debris, not a direct killing method employed by cytotoxic T cells.