Here are the essential concepts you must grasp in order to answer the question correctly.
Wobble Pairing
Wobble pairing refers to the flexibility in base pairing between the third position of a codon in mRNA and the corresponding anticodon in tRNA. This phenomenon allows a single tRNA to recognize multiple codons that code for the same amino acid, contributing to the redundancy of the genetic code. This flexibility helps to minimize the impact of mutations and ensures efficient protein synthesis.
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Codons and tRNAs
Codons are sequences of three nucleotides in mRNA that specify particular amino acids during protein synthesis. There are 64 possible codons, but not all of them correspond to unique tRNAs; in fact, there are fewer than 64 distinct tRNAs due to the wobble effect. This means that multiple codons can be read by the same tRNA, which is crucial for the efficiency of translation.
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Codon Usage
Codon usage refers to the frequency with which different codons are used to encode amino acids in a given organism. While there are 64 codons, not all are utilized in every organism, and some codons may not specify an amino acid at all, serving instead as stop signals. Understanding codon usage is important for comprehending how genetic information is translated into functional proteins.
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