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Multiple Choice
What is the role of calcium in the cross-bridge cycle during muscle contraction?
A
Calcium directly hydrolyzes ATP to provide energy for muscle contraction.
B
Calcium binds to troponin, causing a conformational change that exposes binding sites on actin.
C
Calcium binds to myosin, initiating the power stroke of the cross-bridge cycle.
D
Calcium provides the energy required for the myosin head to detach from actin.
Verified step by step guidance
1
Understand the cross-bridge cycle: The cross-bridge cycle is a series of molecular events that occur during muscle contraction, involving the interaction between actin and myosin filaments.
Identify the role of calcium: Calcium ions play a crucial role in regulating the interaction between actin and myosin by binding to specific proteins.
Focus on troponin: Calcium binds to the protein troponin, which is part of the thin filament structure in muscle fibers.
Explain the conformational change: When calcium binds to troponin, it causes a conformational change in the troponin-tropomyosin complex, which exposes the binding sites on actin for myosin attachment.
Relate to muscle contraction: This exposure of binding sites allows myosin heads to attach to actin, forming cross-bridges, and initiating the power stroke that leads to muscle contraction.