Multiple Choice
In the context of the immune system, what is a naive lymphocyte?
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21. The Immune System
Introduction to the Immune System
Multiple Choice
Which of the following statements is true regarding the interaction between CD40 and CD40 ligand?
A
CD40 ligand is primarily expressed on B cells and interacts with CD40 on T cells.
B
CD40 ligand is a soluble protein that circulates freely in the bloodstream.
C
The interaction between CD40 and CD40 ligand is crucial for B cell activation and antibody production.
D
CD40 is a cytokine that binds to CD40 ligand to initiate apoptosis in immune cells.
Verified step by step guidance1
Understand the roles of CD40 and CD40 ligand in the immune system. CD40 is a receptor found on the surface of B cells, while CD40 ligand (also known as CD40L or CD154) is primarily expressed on activated T cells.
Recognize the importance of the interaction between CD40 and CD40 ligand. This interaction is crucial for the activation of B cells, which leads to their proliferation and differentiation into plasma cells that produce antibodies.
Clarify the incorrect statements: CD40 ligand is not primarily expressed on B cells; it is expressed on T cells. CD40 ligand is not a soluble protein; it is a membrane-bound protein on T cells.
Identify the correct statement: The interaction between CD40 and CD40 ligand is essential for B cell activation and antibody production, which is a key process in the adaptive immune response.
Understand that CD40 is not a cytokine, and its interaction with CD40 ligand does not initiate apoptosis in immune cells. Instead, it promotes survival and activation of B cells.
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