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Multiple Choice
Which of the following statements about the proximal convoluted tubule of the mammalian kidney is accurate?
A
It is primarily responsible for reabsorbing water, ions, and nutrients from the filtrate.
B
It is the main site of urine concentration through the action of antidiuretic hormone (ADH).
C
It is located in the renal medulla.
D
It secretes renin directly into the bloodstream.
Verified step by step guidance
1
Step 1: Begin by identifying the anatomical location and function of the proximal convoluted tubule (PCT) within the nephron. The PCT is located in the renal cortex, not the renal medulla, and is the first segment of the nephron after the glomerulus.
Step 2: Understand the primary role of the PCT. It is responsible for reabsorbing water, ions (such as sodium and chloride), and nutrients (like glucose and amino acids) from the filtrate back into the bloodstream. This process is essential for maintaining homeostasis.
Step 3: Clarify the role of antidiuretic hormone (ADH). ADH primarily acts on the collecting ducts and distal convoluted tubules to concentrate urine, not the PCT. Therefore, the PCT is not the main site of urine concentration through ADH action.
Step 4: Examine the secretion of renin. Renin is secreted by the juxtaglomerular cells of the kidney, not the PCT. The PCT does not directly secrete renin into the bloodstream.
Step 5: Based on the above clarifications, the accurate statement about the PCT is that it is primarily responsible for reabsorbing water, ions, and nutrients from the filtrate. This aligns with its physiological function in the nephron.