How do upper and lower motor neurons differ?
Table of contents
- 1. Introduction to Anatomy & Physiology5h 43m
- What is Anatomy & Physiology?22m
- Levels of Organization13m
- Variation in Anatomy & Physiology12m
- Introduction to Organ Systems27m
- Homeostasis10m
- Feedback Loops11m
- Feedback Loops: Negative Feedback19m
- Feedback Loops: Positive Feedback11m
- Anatomical Position7m
- Introduction to Directional Terms3m
- Directional Terms: Up and Down9m
- Directional Terms: Front and Back6m
- Directional Terms: Body Sides12m
- Directional Terms: Limbs6m
- Directional Terms: Depth Within the Body4m
- Introduction to Anatomical Terms for Body Regions3m
- Anatomical Terms for the Head and Neck8m
- Anatomical Terms for the Front of the Trunk8m
- Anatomical Terms for the Back9m
- Anatomical Terms for the Arm and Hand9m
- Anatomical Terms for the Leg and Foot15m
- Review- Using Anatomical Terms and Directions12m
- Abdominopelvic Quadrants and Regions19m
- Anatomical Planes & Sections17m
- Organization of the Body: Body Cavities13m
- Organization of the Body: Serous Membranes14m
- Organization of the Body: Serous Membrane Locations8m
- Organization of the Body: Thoracic Cavity8m
- Organization of the Body: Abdominopelvic Cavity12m
- 2. Cell Chemistry & Cell Components12h 36m
- Atoms- Smallest Unit of Matter57m
- Isotopes39m
- Introduction to Chemical Bonding19m
- Covalent Bonds40m
- Noncovalent Bonds5m
- Ionic Bonding37m
- Hydrogen Bonding19m
- Introduction to Water7m
- Properties of Water- Cohesion and Adhesion7m
- Properties of Water- Density8m
- Properties of Water- Thermal14m
- Properties of Water- The Universal Solvent17m
- Acids and Bases12m
- pH Scale21m
- Carbon8m
- Functional Groups9m
- Introduction to Biomolecules2m
- Monomers & Polymers11m
- Carbohydrates23m
- Proteins25m
- Nucleic Acids34m
- Lipids28m
- Microscopes11m
- Prokaryotic & Eukaryotic Cells26m
- Introduction to Eukaryotic Organelles14m
- Endomembrane System: Protein Secretion30m
- Endomembrane System: Digestive Organelles14m
- Mitochondria & Chloroplasts21m
- Endosymbiotic Theory10m
- Introduction to the Cytoskeleton11m
- Cell Junctions8m
- Biological Membranes11m
- Types of Membrane Proteins8m
- Concentration Gradients and Diffusion9m
- Introduction to Membrane Transport16m
- Passive vs. Active Transport14m
- Osmosis30m
- Simple and Facilitated Diffusion17m
- Active Transport30m
- Endocytosis and Exocytosis15m
- 3. Energy & Cell Processes10h 6m
- Introduction to Energy15m
- Laws of Thermodynamics15m
- Chemical Reactions9m
- ATP20m
- Enzymes14m
- Enzyme Activation Energy9m
- Enzyme Binding Factors9m
- Enzyme Inhibition10m
- Introduction to Metabolism8m
- Redox Reactions15m
- Introduction to Cellular Respiration22m
- Types of Phosphorylation14m
- Glycolysis19m
- Pyruvate Oxidation8m
- Krebs Cycle16m
- Electron Transport Chain10m
- Chemiosmosis7m
- Review of Aerobic Cellular Respiration19m
- Fermentation & Anaerobic Respiration23m
- Introduction to Cell Division22m
- Organization of DNA in the Cell17m
- Introduction to the Cell Cycle7m
- Interphase18m
- Phases of Mitosis48m
- Cytokinesis16m
- Cell Cycle Regulation18m
- Review of the Cell Cycle7m
- Cancer13m
- Introduction to DNA Replication22m
- DNA Repair8m
- Central Dogma7m
- Introduction to Transcription20m
- Steps of Transcription19m
- Genetic Code25m
- Introduction to Translation30m
- Steps of Translation23m
- Post-Translational Modification6m
- 4. Tissues & Histology10h 3m
- Introduction to Tissues & Histology16m
- Introduction to Epithelial Tissue24m
- Characteristics of Epithelial Tissue37m
- Structural Naming of Epithelial Tissue19m
- Simple Epithelial Tissues1h 2m
- Stratified Epithelial Tissues55m
- Identifying Types of Epithelial Tissue32m
- Glandular Epithelial Tissue26m
- Introduction to Connective Tissue36m
- Classes of Connective Tissue8m
- Introduction to Connective Tissue Proper40m
- Connective Tissue Proper: Loose Connective Tissue56m
- Connective Tissue Proper: Dense Connective Tissue49m
- Specialized Connective Tissue: Cartilage44m
- Specialized Connective Tissue: Bone12m
- Specialized Connective Tissue: Blood9m
- Introduction to Muscle Tissue7m
- Types of Muscle Tissue45m
- Introduction to Nervous Tissue8m
- Nervous Tissue: The Neuron8m
- 5. Integumentary System2h 20m
- 6. Bones & Skeletal Tissue2h 16m
- An Introduction to Bone and Skeletal Tissue18m
- Gross Anatomy of Bone: Compact and Spongy Bone7m
- Gross Anatomy of Bone: Periosteum and Endosteum11m
- Gross Anatomy of Bone: Bone Marrow8m
- Gross Anatomy of Bone: Short, Flat, and Irregular Bones5m
- Gross Anatomy of Bones - Structure of a Long Bone23m
- Microscopic Anatomy of Bones - Bone Matrix9m
- Microscopic Anatomy of Bones - Bone Cells25m
- Microscopic Anatomy of Bones - The Osteon17m
- Microscopic Anatomy of Bones - Trabeculae9m
- 7. The Skeletal System2h 35m
- 8. Joints2h 17m
- 9. Muscle Tissue2h 33m
- 10. Muscles1h 11m
- 11. Nervous Tissue and Nervous System1h 35m
- 12. The Central Nervous System1h 6m
- 13. The Peripheral Nervous System1h 26m
- Introduction to the Peripheral Nervous System5m
- Organization of Sensory Pathways16m
- Introduction to Sensory Receptors5m
- Sensory Receptor Classification by Modality6m
- Sensory Receptor Classification by Location8m
- Proprioceptors7m
- Adaptation of Sensory Receptors8m
- Introduction to Reflex Arcs13m
- Reflex Arcs15m
- 14. The Autonomic Nervous System1h 38m
- 15. The Special Senses2h 41m
- 16. The Endocrine System2h 48m
- 17. The Blood3h 22m
- 18. The Heart3h 42m
- 19. The Blood Vessels3h 35m
- 20. The Lymphatic System3h 16m
- 21. The Immune System14h 37m
- Introduction to the Immune System10m
- Introduction to Innate Immunity17m
- Introduction to First-Line Defenses5m
- Physical Barriers in First-Line Defenses: Skin13m
- Physical Barriers in First-Line Defenses: Mucous Membrane9m
- First-Line Defenses: Chemical Barriers24m
- First-Line Defenses: Normal Microbiota7m
- Introduction to Cells of the Immune System15m
- Cells of the Immune System: Granulocytes28m
- Cells of the Immune System: Agranulocytes26m
- Introduction to Cell Communication5m
- Cell Communication: Surface Receptors & Adhesion Molecules16m
- Cell Communication: Cytokines27m
- Pattern Recognition Receptors (PRRs)48m
- Introduction to the Complement System24m
- Activation Pathways of the Complement System23m
- Effects of the Complement System23m
- Review of the Complement System13m
- Phagocytosis17m
- Introduction to Inflammation18m
- Steps of the Inflammatory Response28m
- Fever8m
- Interferon Response25m
- Review Map of Innate Immunity
- Introduction to Adaptive Immunity32m
- Antigens12m
- Introduction to T Lymphocytes38m
- Major Histocompatibility Complex Molecules20m
- Activation of T Lymphocytes21m
- Functions of T Lymphocytes25m
- Review of Cytotoxic vs Helper T Cells13m
- Introduction to B Lymphocytes27m
- Antibodies14m
- Classes of Antibodies35m
- Outcomes of Antibody Binding to Antigen15m
- T Dependent & T Independent Antigens21m
- Clonal Selection20m
- Antibody Class Switching17m
- Affinity Maturation14m
- Primary and Secondary Response of Adaptive Immunity21m
- Immune Tolerance28m
- Regulatory T Cells10m
- Natural Killer Cells16m
- Review of Adaptive Immunity25m
- 22. The Respiratory System3h 20m
- 23. The Digestive System2h 5m
- 24. Metabolism and Nutrition4h 0m
- Essential Amino Acids5m
- Lipid Vitamins19m
- Cellular Respiration: Redox Reactions15m
- Introduction to Cellular Respiration22m
- Cellular Respiration: Types of Phosphorylation14m
- Cellular Respiration: Glycolysis19m
- Cellular Respiration: Pyruvate Oxidation8m
- Cellular Respiration: Krebs Cycle16m
- Cellular Respiration: Electron Transport Chain14m
- Cellular Respiration: Chemiosmosis7m
- Review of Aerobic Cellular Respiration18m
- Fermentation & Anaerobic Respiration23m
- Gluconeogenesis16m
- Fatty Acid Oxidation20m
- Amino Acid Oxidation17m
- 25. The Urinary System2h 39m
- 26. Fluid and Electrolyte Balance, Acid Base Balance37m
- 27. The Reproductive System2h 5m
- 28. Human Development1h 21m
- 29. Heredity3h 32m
13. The Peripheral Nervous System
Organization of Sensory Pathways
Problem L3.3
Textbook Question
When Mr. Williams goes to the emergency department with pain in the area along the midline of the diaphragm, he worries he is having a heart attack. Could the pain be related to his heart? Could it be related to any other organ(s)? Explain.

1
Understand the location of the pain: The diaphragm is a dome-shaped muscle located at the base of the thoracic cavity, separating it from the abdominal cavity. Pain along the midline of the diaphragm could be referred pain from organs in the thoracic or abdominal regions.
Consider the possibility of cardiac involvement: Pain in the midline of the diaphragm could be related to the heart, as cardiac pain (e.g., from a heart attack or angina) is often referred to areas such as the chest, left arm, jaw, or even the epigastric region (upper abdomen). This is due to shared nerve pathways between the heart and these regions.
Evaluate other potential causes: The diaphragm is in close proximity to several other organs, including the stomach, esophagus, liver, and lungs. Pain in this area could also be related to conditions such as gastroesophageal reflux disease (GERD), a hiatal hernia, or even issues with the liver or gallbladder.
Understand referred pain mechanisms: Referred pain occurs when pain from one organ is perceived in a different location due to shared sensory pathways in the spinal cord. For example, irritation of the diaphragm (e.g., from inflammation or pressure) can cause referred pain to the shoulder or upper abdomen because of the phrenic nerve (C3-C5).
Recommend further evaluation: To determine the exact cause of the pain, a healthcare provider would likely perform diagnostic tests such as an electrocardiogram (ECG) to rule out cardiac issues, imaging studies (e.g., X-ray, ultrasound, or CT scan) to assess nearby organs, and possibly blood tests to check for markers of inflammation or organ dysfunction.

This video solution was recommended by our tutors as helpful for the problem above
Play a video:
Was this helpful?
Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Referred Pain
Referred pain occurs when pain is perceived in an area of the body that is not the source of the pain. This phenomenon can happen because of the way nerves from different organs converge in the spinal cord. For instance, pain from the diaphragm can be felt in the shoulder or chest, which may lead Mr. Williams to mistakenly associate his symptoms with a heart attack.
Recommended video:
The Cerebrum Example 3
Diaphragm Anatomy and Function
The diaphragm is a dome-shaped muscle that separates the thoracic cavity from the abdominal cavity and plays a crucial role in respiration. It is innervated by the phrenic nerve and can be affected by various conditions, including irritation or injury, which can cause pain in the midline area. Understanding its anatomy helps in identifying potential sources of pain that may not be cardiac in nature.
Recommended video:
Functional Groups
Cardiac vs. Non-Cardiac Chest Pain
Differentiating between cardiac and non-cardiac chest pain is essential for accurate diagnosis. Cardiac pain is often associated with conditions like angina or myocardial infarction, while non-cardiac pain can arise from gastrointestinal, musculoskeletal, or pulmonary issues. Recognizing the characteristics of the pain, such as its location, quality, and associated symptoms, can help determine the underlying cause.
Recommended video:
Guided course
Events in the Cardiac Cycle
Watch next
Master Somatosensory System with a bite sized video explanation from Bruce Bryan
Start learningRelated Videos
Related Practice
Textbook Question
516
views