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Multiple Choice
Which of the following statements about the repair of thymine dimers is true?
A
Thymine dimers are repaired by the process of nucleotide excision repair.
B
Thymine dimers are repaired by the process of base excision repair.
C
Thymine dimers are repaired by the process of homologous recombination.
D
Thymine dimers are repaired by the process of mismatch repair.
Verified step by step guidance
1
Understand what thymine dimers are: Thymine dimers are a type of DNA damage caused by ultraviolet (UV) light, where two adjacent thymine bases bond together, disrupting the DNA structure.
Learn about nucleotide excision repair: This is a DNA repair mechanism that removes bulky lesions, such as thymine dimers, by excising a short single-stranded DNA segment containing the damage.
Differentiate between repair processes: Base excision repair typically fixes small, non-helix-distorting base lesions, while mismatch repair corrects errors that occur during DNA replication. Homologous recombination is involved in repairing double-strand breaks.
Identify the correct repair process for thymine dimers: Nucleotide excision repair is specifically designed to handle the type of damage caused by thymine dimers, making it the correct answer.
Review the steps of nucleotide excision repair: The process involves recognition of the damage, excision of the damaged DNA segment, synthesis of a new DNA strand using the undamaged strand as a template, and ligation to restore the DNA structure.