Textbook Question
Write a single sentence, using no more than 25 words, to summarize each of the following cellular processes:
DNA synthesis
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3. Energy & Cell Processes
Introduction to DNA Replication
Multiple Choice
What is the function of the enzyme topoisomerase in DNA replication?
A
Relieving strain in the DNA ahead of the replication fork caused by the untwisting of the double helix.
B
Elongating new DNA at a replication fork by adding nucleotides to the existing chain.
C
Reattaching the hydrogen bonds between the base pairs in the double helix.
D
Building RNA primers using the parental DNA strand as a template.
Verified step by step guidance1
Understand the context of DNA replication: DNA replication is the process by which a cell duplicates its DNA, ensuring that each new cell receives a complete set of genetic instructions.
Identify the role of topoisomerase: Topoisomerase is an enzyme that helps manage the topology of DNA during replication. It alleviates the tension and strain caused by the unwinding of the DNA double helix.
Recognize the problem caused by unwinding: As the DNA helix unwinds, it creates supercoiling and tension ahead of the replication fork, which can hinder the progress of replication.
Explain how topoisomerase functions: Topoisomerase works by cutting one or both strands of the DNA, allowing it to rotate and relieve the tension, and then rejoining the strands. This action prevents the DNA from becoming too tightly coiled.
Clarify the importance of topoisomerase: By relieving the strain ahead of the replication fork, topoisomerase ensures smooth progression of the replication machinery, facilitating the accurate and efficient duplication of DNA.
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