Here are the essential concepts you must grasp in order to answer the question correctly.
HIV and its Target Cells
HIV (Human Immunodeficiency Virus) primarily targets the immune system, specifically the CD4+ T cells, commonly known as Helper T cells. These cells play a crucial role in orchestrating the immune response by activating other immune cells. The virus binds to the CD4 receptor and co-receptors on these cells, leading to their infection and eventual depletion, which compromises the immune system.
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Helper T Cells
Helper T cells are a subset of T lymphocytes that are essential for the adaptive immune response. They assist in activating B cells to produce antibodies and stimulate cytotoxic T cells to kill infected cells. The loss of Helper T cells due to HIV infection leads to a weakened immune system, making the body more susceptible to opportunistic infections and diseases.
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Immune System Response
The immune system response involves various cells and mechanisms that work together to defend the body against pathogens. This includes the innate immune response, which provides immediate defense, and the adaptive immune response, which is more specific and involves memory cells. Understanding how HIV disrupts this response, particularly by targeting Helper T cells, is crucial for comprehending the implications of HIV infection and the progression to AIDS.
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