People with allergies commonly take antihistamines with decongestants to relieve their symptoms. The container warns that individuals who are being treated for high blood pressure should not take the medication. Why not?
Table of contents
- 1. Introduction to Anatomy & Physiology5h 43m
- What is Anatomy & Physiology?22m
- Levels of Organization13m
- Variation in Anatomy & Physiology12m
- Introduction to Organ Systems27m
- Homeostasis10m
- Feedback Loops11m
- Feedback Loops: Negative Feedback19m
- Feedback Loops: Positive Feedback11m
- Anatomical Position7m
- Introduction to Directional Terms3m
- Directional Terms: Up and Down9m
- Directional Terms: Front and Back6m
- Directional Terms: Body Sides12m
- Directional Terms: Limbs6m
- Directional Terms: Depth Within the Body4m
- Introduction to Anatomical Terms for Body Regions3m
- Anatomical Terms for the Head and Neck8m
- Anatomical Terms for the Front of the Trunk8m
- Anatomical Terms for the Back9m
- Anatomical Terms for the Arm and Hand9m
- Anatomical Terms for the Leg and Foot15m
- Review- Using Anatomical Terms and Directions12m
- Abdominopelvic Quadrants and Regions19m
- Anatomical Planes & Sections17m
- Organization of the Body: Body Cavities13m
- Organization of the Body: Serous Membranes14m
- Organization of the Body: Serous Membrane Locations8m
- Organization of the Body: Thoracic Cavity8m
- Organization of the Body: Abdominopelvic Cavity12m
- 2. Cell Chemistry & Cell Components12h 36m
- Atoms- Smallest Unit of Matter57m
- Isotopes39m
- Introduction to Chemical Bonding19m
- Covalent Bonds40m
- Noncovalent Bonds5m
- Ionic Bonding37m
- Hydrogen Bonding19m
- Introduction to Water7m
- Properties of Water- Cohesion and Adhesion7m
- Properties of Water- Density8m
- Properties of Water- Thermal14m
- Properties of Water- The Universal Solvent17m
- Acids and Bases12m
- pH Scale21m
- Carbon8m
- Functional Groups9m
- Introduction to Biomolecules2m
- Monomers & Polymers11m
- Carbohydrates23m
- Proteins25m
- Nucleic Acids34m
- Lipids28m
- Microscopes11m
- Prokaryotic & Eukaryotic Cells26m
- Introduction to Eukaryotic Organelles14m
- Endomembrane System: Protein Secretion30m
- Endomembrane System: Digestive Organelles14m
- Mitochondria & Chloroplasts21m
- Endosymbiotic Theory10m
- Introduction to the Cytoskeleton11m
- Cell Junctions8m
- Biological Membranes11m
- Types of Membrane Proteins8m
- Concentration Gradients and Diffusion9m
- Introduction to Membrane Transport16m
- Passive vs. Active Transport14m
- Osmosis30m
- Simple and Facilitated Diffusion17m
- Active Transport30m
- Endocytosis and Exocytosis15m
- 3. Energy & Cell Processes10h 6m
- Introduction to Energy15m
- Laws of Thermodynamics15m
- Chemical Reactions9m
- ATP20m
- Enzymes14m
- Enzyme Activation Energy9m
- Enzyme Binding Factors9m
- Enzyme Inhibition10m
- Introduction to Metabolism8m
- Redox Reactions15m
- Introduction to Cellular Respiration22m
- Types of Phosphorylation14m
- Glycolysis19m
- Pyruvate Oxidation8m
- Krebs Cycle16m
- Electron Transport Chain10m
- Chemiosmosis7m
- Review of Aerobic Cellular Respiration19m
- Fermentation & Anaerobic Respiration23m
- Introduction to Cell Division22m
- Organization of DNA in the Cell17m
- Introduction to the Cell Cycle7m
- Interphase18m
- Phases of Mitosis48m
- Cytokinesis16m
- Cell Cycle Regulation18m
- Review of the Cell Cycle7m
- Cancer13m
- Introduction to DNA Replication22m
- DNA Repair8m
- Central Dogma7m
- Introduction to Transcription20m
- Steps of Transcription19m
- Genetic Code25m
- Introduction to Translation30m
- Steps of Translation23m
- Post-Translational Modification6m
- 4. Tissues & Histology10h 3m
- Introduction to Tissues & Histology16m
- Introduction to Epithelial Tissue24m
- Characteristics of Epithelial Tissue37m
- Structural Naming of Epithelial Tissue19m
- Simple Epithelial Tissues1h 2m
- Stratified Epithelial Tissues55m
- Identifying Types of Epithelial Tissue32m
- Glandular Epithelial Tissue26m
- Introduction to Connective Tissue36m
- Classes of Connective Tissue8m
- Introduction to Connective Tissue Proper40m
- Connective Tissue Proper: Loose Connective Tissue56m
- Connective Tissue Proper: Dense Connective Tissue49m
- Specialized Connective Tissue: Cartilage44m
- Specialized Connective Tissue: Bone12m
- Specialized Connective Tissue: Blood9m
- Introduction to Muscle Tissue7m
- Types of Muscle Tissue45m
- Introduction to Nervous Tissue8m
- Nervous Tissue: The Neuron8m
- 5. Integumentary System2h 20m
- 6. Bones & Skeletal Tissue2h 16m
- An Introduction to Bone and Skeletal Tissue18m
- Gross Anatomy of Bone: Compact and Spongy Bone7m
- Gross Anatomy of Bone: Periosteum and Endosteum11m
- Gross Anatomy of Bone: Bone Marrow8m
- Gross Anatomy of Bone: Short, Flat, and Irregular Bones5m
- Gross Anatomy of Bones - Structure of a Long Bone23m
- Microscopic Anatomy of Bones - Bone Matrix9m
- Microscopic Anatomy of Bones - Bone Cells25m
- Microscopic Anatomy of Bones - The Osteon17m
- Microscopic Anatomy of Bones - Trabeculae9m
- 7. The Skeletal System2h 35m
- 8. Joints2h 17m
- 9. Muscle Tissue2h 33m
- 10. Muscles1h 11m
- 11. Nervous Tissue and Nervous System1h 35m
- 12. The Central Nervous System1h 6m
- 13. The Peripheral Nervous System1h 26m
- Introduction to the Peripheral Nervous System5m
- Organization of Sensory Pathways16m
- Introduction to Sensory Receptors5m
- Sensory Receptor Classification by Modality6m
- Sensory Receptor Classification by Location8m
- Proprioceptors7m
- Adaptation of Sensory Receptors8m
- Introduction to Reflex Arcs13m
- Reflex Arcs15m
- 14. The Autonomic Nervous System1h 38m
- 15. The Special Senses2h 41m
- 16. The Endocrine System2h 48m
- 17. The Blood3h 22m
- 18. The Heart3h 42m
- 19. The Blood Vessels3h 35m
- 20. The Lymphatic System3h 16m
- 21. The Immune System14h 37m
- Introduction to the Immune System10m
- Introduction to Innate Immunity17m
- Introduction to First-Line Defenses5m
- Physical Barriers in First-Line Defenses: Skin13m
- Physical Barriers in First-Line Defenses: Mucous Membrane9m
- First-Line Defenses: Chemical Barriers24m
- First-Line Defenses: Normal Microbiota7m
- Introduction to Cells of the Immune System15m
- Cells of the Immune System: Granulocytes28m
- Cells of the Immune System: Agranulocytes26m
- Introduction to Cell Communication5m
- Cell Communication: Surface Receptors & Adhesion Molecules16m
- Cell Communication: Cytokines27m
- Pattern Recognition Receptors (PRRs)48m
- Introduction to the Complement System24m
- Activation Pathways of the Complement System23m
- Effects of the Complement System23m
- Review of the Complement System13m
- Phagocytosis17m
- Introduction to Inflammation18m
- Steps of the Inflammatory Response28m
- Fever8m
- Interferon Response25m
- Review Map of Innate Immunity
- Introduction to Adaptive Immunity32m
- Antigens12m
- Introduction to T Lymphocytes38m
- Major Histocompatibility Complex Molecules20m
- Activation of T Lymphocytes21m
- Functions of T Lymphocytes25m
- Review of Cytotoxic vs Helper T Cells13m
- Introduction to B Lymphocytes27m
- Antibodies14m
- Classes of Antibodies35m
- Outcomes of Antibody Binding to Antigen15m
- T Dependent & T Independent Antigens21m
- Clonal Selection20m
- Antibody Class Switching17m
- Affinity Maturation14m
- Primary and Secondary Response of Adaptive Immunity21m
- Immune Tolerance28m
- Regulatory T Cells10m
- Natural Killer Cells16m
- Review of Adaptive Immunity25m
- 22. The Respiratory System3h 20m
- 23. The Digestive System2h 5m
- 24. Metabolism and Nutrition4h 0m
- Essential Amino Acids5m
- Lipid Vitamins19m
- Cellular Respiration: Redox Reactions15m
- Introduction to Cellular Respiration22m
- Cellular Respiration: Types of Phosphorylation14m
- Cellular Respiration: Glycolysis19m
- Cellular Respiration: Pyruvate Oxidation8m
- Cellular Respiration: Krebs Cycle16m
- Cellular Respiration: Electron Transport Chain14m
- Cellular Respiration: Chemiosmosis7m
- Review of Aerobic Cellular Respiration18m
- Fermentation & Anaerobic Respiration23m
- Gluconeogenesis16m
- Fatty Acid Oxidation20m
- Amino Acid Oxidation17m
- 25. The Urinary System2h 39m
- 26. Fluid and Electrolyte Balance, Acid Base Balance37m
- 27. The Reproductive System2h 5m
- 28. Human Development1h 21m
- 29. Heredity3h 32m
19. The Blood Vessels
Introduction to Hemodynamics
Problem L3.4
Textbook Question
Explain why the skin and lips of fair-skinned individuals may 'turn blue' in very cold weather.

1
Understand the concept of cyanosis: Cyanosis is a condition where the skin or mucous membranes turn blue due to insufficient oxygen in the blood. This can occur when blood flow is reduced or oxygen delivery is impaired.
Recognize the role of temperature in blood vessel constriction: In cold weather, the body conserves heat by constricting blood vessels in the skin (a process called vasoconstriction). This reduces blood flow to the skin and extremities to maintain core body temperature.
Explain the impact of reduced blood flow on oxygen delivery: When blood flow to the skin is reduced, less oxygenated blood reaches the surface tissues. This can cause the skin to appear blue, especially in areas like the lips, which have thinner skin and are more vascularized.
Discuss the role of hemoglobin and light absorption: Hemoglobin in the blood reflects light differently depending on its oxygenation state. Deoxygenated hemoglobin absorbs more red light and reflects blue light, contributing to the bluish appearance of the skin and lips.
Connect the phenomenon to fair-skinned individuals: Fair-skinned individuals may show this bluish tint more prominently because their skin has less melanin, which can mask the underlying color changes caused by reduced oxygenation.

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Key Concepts
Here are the essential concepts you must grasp in order to answer the question correctly.
Vasoconstriction
Vasoconstriction is the narrowing of blood vessels, which occurs in response to cold temperatures. This physiological response reduces blood flow to the skin and extremities to conserve body heat. In fair-skinned individuals, this can lead to a noticeable decrease in blood circulation, causing the skin and lips to appear bluish due to the reduced oxygenated blood reaching the surface.
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Vasoconstriction & Vasodilation
Cyanosis
Cyanosis is a condition characterized by a bluish discoloration of the skin and mucous membranes, resulting from insufficient oxygen in the blood. When blood flow is restricted due to vasoconstriction, the oxygen levels in the blood decrease, leading to cyanosis. This is particularly visible in fair-skinned individuals, where the contrast between the skin tone and the bluish hue is more pronounced.
Thermoregulation
Thermoregulation is the process by which the body maintains its core internal temperature. In cold environments, the body employs various mechanisms, including vasoconstriction and shivering, to preserve heat. Fair-skinned individuals may be more susceptible to temperature changes, making their skin and lips more likely to exhibit signs of cold stress, such as turning blue, as the body prioritizes vital organ function over peripheral circulation.
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Introduction to Thermoregulation
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