Table of contents

1. Introduction to Anatomy & Physiology5h 43m
2. Cell Chemistry & Cell Components12h 36m
3. Energy & Cell Processes10h 6m
4. Tissues & Histology10h 3m
5. Integumentary System2h 20m
6. Bones & Skeletal Tissue2h 16m
7. The Skeletal System2h 35m
8. Joints2h 17m
9. Muscle Tissue2h 33m
10. Muscles1h 11m
11. Nervous Tissue and Nervous System1h 35m
12. The Central Nervous System1h 6m
- Introduction to the Central Nervous System
  18m
- The Cerebrum
  48m
13. The Peripheral Nervous System1h 26m
14. The Autonomic Nervous System1h 38m
15. The Special Senses2h 41m
16. The Endocrine System2h 48m
17. The Blood3h 22m
18. The Heart3h 42m
19. The Blood Vessels3h 35m
20. The Lymphatic System3h 16m
21. The Immune System14h 37m
22. The Respiratory System3h 20m
23. The Digestive System2h 5m
24. Metabolism and Nutrition4h 0m
25. The Urinary System2h 39m
26. Fluid and Electrolyte Balance, Acid Base Balance37m
27. The Reproductive System2h 5m
28. Human Development1h 21m
29. Heredity3h 32m

21. The Immune System

Clonal Selection

Anatomy & Physiology

21. The Immune System

Clonal Selection

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Multiple Choice

The clonal selection theory states that:

Self-reacting T cells are destroyed in the bone marrow.

B cells will only proliferate during an infection if their BCRs successfully bind to the pathogen.

Antibody structure changes as it encounters an antigen for higher specificity binding.

Each T cell produces many different types of antibodies.

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Verified step by step guidance

Understand the clonal selection theory, which is a fundamental concept in immunology explaining how specific immune cells are activated and proliferate in response to an antigen.

Recognize that B cells and T cells are types of lymphocytes involved in the adaptive immune response. B cells are responsible for producing antibodies, while T cells have various roles including helping B cells and directly killing infected cells.

Identify that the clonal selection theory involves the selection and proliferation of specific B cells. This occurs when B cell receptors (BCRs) on the surface of B cells bind to a specific antigen, leading to the activation and proliferation of those B cells.

Note that the statement 'B cells will only proliferate during an infection if their BCRs successfully bind to the pathogen' aligns with the clonal selection theory. This is because only B cells with receptors specific to the pathogen will be selected to proliferate and produce antibodies.

Clarify that the other statements are incorrect: Self-reacting T cells are typically destroyed in the thymus, not the bone marrow; antibody structure does not change upon encountering an antigen, but rather, the diversity of antibodies is generated through genetic recombination; each T cell does not produce antibodies, as this is the role of B cells.