Here are the essential concepts you must grasp in order to answer the question correctly.
ATP Synthase
ATP synthase is an enzyme complex located in the inner mitochondrial membrane that synthesizes adenosine triphosphate (ATP) from adenosine diphosphate (ADP) and inorganic phosphate (Pi). It operates by utilizing the energy derived from a proton (H+) gradient, which is established during oxidative phosphorylation, to drive the phosphorylation of ADP into ATP.
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Electron Transport Chain (ETC)
The electron transport chain is a series of protein complexes and other molecules located in the inner mitochondrial membrane that facilitate the transfer of electrons from electron donors like NADH and FADH2 to electron acceptors. This process releases energy, which is used to pump protons across the membrane, creating a proton gradient essential for ATP synthesis.
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Proton Gradient
A proton gradient refers to the difference in proton concentration across a membrane, which is crucial for ATP production during oxidative phosphorylation. The gradient is generated by the ETC as protons are pumped from the mitochondrial matrix into the intermembrane space, creating potential energy that ATP synthase harnesses to convert ADP and Pi into ATP as protons flow back into the matrix.
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Concentration Gradients and Diffusion