Ch. 5 The Integumentary System

Marieb - Human Anatomy & Physiology 7th Edition

Marieb, Hoehn7th EditionHuman Anatomy & PhysiologyISBN: 9780805359091Not the one you use?Change textbook

Marieb, Hoehn 7th Edition

Ch. 5 The Integumentary System

Problem 13

Chapter 5, Problem 13

Which epidermal cells contain keratohyaline and lamellar granules?

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Understand that the epidermis is composed of several layers of cells, each with distinct functions and characteristics.

Recall that keratohyaline granules are involved in the process of keratinization, helping to form the dense protein matrix in the skin's outer layer.

Recognize that lamellar granules contain lipids that contribute to the skin's waterproof barrier by filling spaces between cells.

Identify the specific epidermal cell type that contains both keratohyaline and lamellar granules; these are the cells in the stratum granulosum layer.

Conclude that the keratinocytes in the stratum granulosum are the epidermal cells containing keratohyaline and lamellar granules, playing a key role in skin barrier formation.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Epidermal Cell Types

The epidermis consists of several cell types, including keratinocytes, melanocytes, Langerhans cells, and Merkel cells. Keratinocytes are the most abundant and are responsible for producing keratin and other granules essential for skin barrier function.

Keratohyaline Granules

Keratohyaline granules are dense, protein-rich structures found in the granular layer of keratinocytes. They contain profilaggrin, which helps in the aggregation of keratin filaments, contributing to the formation of the skin’s protective outer layer.

Lamellar Granules

Lamellar granules are lipid-containing organelles in keratinocytes that release lipids into the extracellular space. These lipids form a waterproof barrier, preventing water loss and protecting the skin from external environmental damage.

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Related Practice

Textbook Question

Which is not a true statement about the papillary dermis?

a. It is largely areolar connective tissue

b. It is most responsible for the toughness of the skin

c. It contains nerve endings that respond to stimuli

d. It is highly vascular

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Textbook Question

Mrs. Gaucher received second-degree burns on her abdomen when she dropped a kettle of boiling water. She asked her doctor (worriedly) if she would need a skin graft. What do you think he told her?

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Textbook Question

The rule of nines is helpful clinically in

a. Diagnosing skin cancer

b. Estimating the extent of a burn

c. Estimating how serious a cancer is

d. Preventing acne