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Activation of T Lymphocytes quiz
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What types of MHC molecules do dendritic cells possess?
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What types of MHC molecules do dendritic cells possess?
Dendritic cells possess both MHC class 1 and MHC class 2 molecules.
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What types of MHC molecules do dendritic cells possess?
Dendritic cells possess both MHC class 1 and MHC class 2 molecules.
Which T cell type is activated by MHC class 1 on dendritic cells?
MHC class 1 activates naive cytotoxic T cells.
Which T cell type is activated by MHC class 2 on dendritic cells?
MHC class 2 activates naive helper T cells.
What happens to T cells after activation by dendritic cells?
Activated T cells proliferate and differentiate into effector T cells or memory T cells.
When do dendritic cells produce co-stimulatory molecules?
Dendritic cells produce co-stimulatory molecules only when presenting harmful antigens.
What is the function of co-stimulatory molecules in T cell activation?
Co-stimulatory molecules signal danger to naive T cells, enhancing their activation.
What is required for naive T cell activation?
Naive T cells require both a harmful antigen and co-stimulatory molecules for activation.
What happens if a dendritic cell presents a harmless antigen?
If a harmless antigen is presented, dendritic cells do not produce co-stimulatory molecules.
What is the fate of naive T cells exposed to harmless antigens without co-stimulatory molecules?
Naive T cells become anergic (unresponsive) and undergo apoptosis.
Why is it important for T cells to become anergic in response to harmless antigens?
This prevents immune responses against harmless antigens, protecting healthy host cells.
What does the term 'anergic' mean in the context of T cells?
Anergic refers to T cells that are unresponsive and do not activate.
What is the outcome for anergic T cells?
Anergic T cells undergo apoptosis, eliminating them from the immune system.
How does the comic strip illustrate T cell activation?
It shows harmful antigens activating T cells, while harmless antigens lead to T cell inactivation.
What immune response is generated when T cells are activated by harmful antigens?
Activated T cells generate an immune response to eliminate the dangerous antigen.
What ensures that the immune system targets only dangerous antigens?
The requirement for co-stimulatory molecules and harmful antigens ensures only dangerous antigens are targeted.