Introduction to T Lymphocytes definitions Flashcards
Introduction to T Lymphocytes definitions
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T Lymphocytes
Crucial cells in adaptive immunity, targeting intracellular pathogens through cell-mediated responses.Thymus
Primary lymphoid organ where T cells develop before migrating to secondary lymphoid organs.Cytotoxic T Cells
T cells responsible for inducing apoptosis in cells infected with intracellular pathogens.Helper T Cells
T cells that aid in activating other immune cells by producing cytokines.Antigen-Presenting Cells
Cells like dendritic cells that present antigens to T cells for activation.T Cell Receptors (TCRs)
Receptors on T cells that recognize specific antigens presented by antigen-presenting cells.Alpha and Beta Chains
Polypeptide chains in TCRs linked by disulfide bonds, crucial for antigen recognition.Variable Region
Part of TCRs that varies between different receptors and binds to specific antigens.Constant Region
Part of TCRs that remains relatively unchanged and is located near the cell surface.Naive T Cells
Inactive T cells that have not yet encountered their specific antigen.Effector T Cells
Short-lived T cells that respond immediately to infections upon activation.Memory T Cells
Long-lived T cells that provide a rapid response to subsequent exposures to the same antigen.CD8
Protein marker on cytotoxic T cells used to identify and dictate their function.CD4
Protein marker on helper T cells used to identify and dictate their function.Cytokines
Signaling proteins produced by helper T cells to activate other immune cells.