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T Dependent & T Independent Antigens definitions
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B cell activation
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B cell activation
The process by which B cells become activated to respond to antigens, involving either T dependent or T independent pathways.
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Terms in this set (15)
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B cell activation
The process by which B cells become activated to respond to antigens, involving either T dependent or T independent pathways.
T dependent antigens
Antigens that require helper T cells for B cell activation, involving a multi-step process including antigen presentation on MHC class II.
T independent antigens
Antigens capable of activating B cells without helper T cells, often long polysaccharides with repeating subunits.
Helper T cells
Immune cells that assist in the activation of B cells by recognizing antigens presented on MHC class II molecules.
Naive B cells
Inactive B cells that have not yet encountered an antigen and require activation to respond to pathogens.
B cell receptors (BCRs)
Molecules on B cell surfaces that bind to specific antigens, initiating the activation process.
MHC class II molecules
Proteins on B cell surfaces that present processed antigen fragments to helper T cells for recognition.
Cytokines
Signaling molecules released by helper T cells to activate B cells during immune responses.
Plasma cells
Differentiated B cells that secrete antibodies to neutralize pathogens.
Memory B cells
B cells that remain after an infection to provide a faster response upon re-exposure to the same antigen.
Polysaccharides
Long carbohydrate molecules with repeating subunits, often forming T independent antigens.
Immune response
The body's defense mechanism against pathogens, involving B cell activation and antibody production.
Pathogens
Microorganisms that cause disease, targeted by the immune system through B cell activation.
Antibodies
Proteins produced by plasma cells that bind to antigens to neutralize or mark them for destruction.
T cell receptors (TCRs)
Molecules on T cells that recognize antigens presented by MHC class II molecules on B cells.