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Endochondral Ossification Process

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  • Cartilage model is formed & enlarges

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  • Compact bone formed along diaphysis (collar)

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  • 1.     Cartilage in diaphysis becomes calcified & chondrocytes die

    a.     remaining cartilage continues to grow

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  • 1.     Spongy bone formed inside diaphysis

    a.     blood vessels & cells penetrate calcified cartilage

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  • As bone continues to elongate, medullary cavity forms

    interior spongy bone is dissolved by osteoclasts

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  •   Spongy bone forms in epiphyses (secondary ossification only in long bones)

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  • Epiphyses fill with spongy bone

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