Exam 3-respiratory, immunity, and lymphatic
Terms in this set (48)
What are the two major functions of the lymphatic system?
Produce, maintain, and distribute lymphocytes; return interstitial fluid to the blood.
What is lymph?
Interstitial fluid that has entered lymphatic capillaries.
Where are lymphatic capillaries found?
In interstitial spaces.
Are lymphatic capillaries open-ended or closed-ended?
Closed-ended.
The two major lymphatic ducts are the
Thoracic duct and right lymphatic duct.
Lymphatic vessels are most similar to what blood vessels?
Veins.
Where do all lymphocytes originate?
red bone marrow
What does the "T" in T cells stand for?
Thymus-dependent.
What do T cells bind to?
Cells with a specific antigen.
Where do B cells mature?
bone marrow
What is the major function of B cells?
Secrete antibodies against a specific antigen.
What do NK cells attack?
Foreign, abnormal, or infected cells
What is an antigen?
A substance that provokes an adaptive immune response.
What do antigens stimulate the production of?
Antibodies.
Lymphoid tissue consists mainly of what cells?
Lymphocytes (mostly B cells).
What type of connective tissue contains lymphoid nodules?
Areolar or reticular CT.
What does MALT stand for?
Mucosa-Associated Lymphatic Tissue.
Where is MALT found?
Along the digestive tract.
What are tonsils?
Large lymphatic nodules in the pharynx.
What cells are abundant in lymph nodes?
Lymphocytes and macrophages.
What surrounds a lymph node?
A capsule
Where are lymph nodes concentrated?
Axillary, cervical, and inguinal regions.
How many afferent vessels enter a lymph node?
multiple
How many efferent vessels leave a lymph node?
one or two
What is the primary function of lymph nodes?
remove antigens from lymph
What does the spleen remove antigens from?
blood
Besides immune function, what does the spleen store?
Iron (Fe)
What cells are abundant in the spleen?
Macrophages
What happens to the thymus after puberty?
It decreases in size
where do t-cells mature?
thymus gland
What are the first-line defenses against pathogens?
epidermis and mucous membranes
What process attracts phagocytes to an area?
chemotaxis
Which cells are the major phagocytes?
neutrophils and macrophages
What is opsonization?
coating pathogens to enhance phagocytosis
What do NK cells recognize?
Cells with abnormal or missing membrane markers.
What three substances do NK cells secrete?
Perforin, granzymes, and TNF.
What chemical is most associated with vasodilation during inflammation?
histamine
Inflammation causes increased:
Vasodilation, permeability, and phagocyte activity.
What do interferons do?
Stimulate antiviral proteins and activate NK cells/macrophages.
Humoral immunity is mediated by what cells?
B cells
What is the role of Regulatory T cells (Treg)?
Suppress b cell and t cell activity
What are the four major functions of the respiratory system?
External respiration, protection, olfaction, and vocalization.
What type of epithelium makes up most of the respiratory mucosa?
Pseudostratified ciliated columnar epithelium.
What connective tissue layer lies beneath the respiratory epithelium?
Lamina propria.
What direction is mucus swept in the respiratory tract?
toward the pharynx.
What is the function of the pharynx?
Passageway for food and air.
What type of muscle controls the pharynx?
Skeletal muscle.
What is another name for the larynx?
voice box