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Lab 7 Histology

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  • Squamous cell


    Flat cell with bulging nucleus

  • Cuboidal


    Cube shaped cell, round centered nucleus

  • Columnar


    Nucleus is elongated and close to the basal surface

  • Simple Epithelium


    single layer of cells

  • Stratified Epithelium


    2+ cell layers

  • Pseudostratified Epithelium


    Single layer of cells with differing heights

  • Simple Squamous Epithelium


    Function: allow materials to pass by diffusion and filtration in sites where protection is not important

    Location: air sacs of the lungs

  • Simple Cuboidal Epithelium


    Functions: secretion & absorption

    Location: kidney tubules & ovary surface

  • Simple Columnar Epithelium


    Function: absorption, secretion of mucus and other substances

    Location: nonciliated lines most of digestive tract (gallbladder); ciliated is in uterine tubes

  • Pseudostratified Ciliated Columnar Epithelium


    Function: secrete mucus to trap dust and propel it away from lungs

    Location: respiratory system

  • Non Keratinized Squamous Epithelium


    Function: protect from abrasions in moist areas

    Location: oral cavity

  • Keratinized Stratified Squamous Epithelium


    Function: Protect from abrasions, toughen and waterproof skin.

    Location: epidermis

  • Transitional Epithelium


    Function: stretches readily, permits stored urine to distend urinary organ

    Location: ureters & bladder

  • What are Goblet Cells?


    Specialized epithelial cells that secrete mucus to protect and lubricate.

  • What epithelial tissues have goblet cells?


    Goblet cells are in simple columnar epithelial tissue

  • What are Cilia? Function? Location?


    Hair-like projections attached to tissue; help move substances along;

    Location: Pseudostratified columnar Epithelium in respiratory system

  • What are microvilli? Function? Location?


    projections found on the surface of epithelial cells

    Function: increase surface area to enhance absorption

    Location: epithelial tissue in the small intestine

  • Basement membrane


    Thin specialized layer made of extracellular matrix; has the basal lamina and reticular lamina

  • Difference between simple and stratified epithelium relative to the basement membrane?


    Simple epithelium consists of a single cell layer attached to the basement membrane.

    Stratified epithelium has multiple cell layers with only one layer being attached to the basement membrane.

  • Difference between stratified squamous and transitional epithelium?


    Stratified squamous only has squamous cells; transitional epithelium has both columnar and cuboidal cells

  • What type of tissue are the visceral and serous membranes made of?


    Mesothelium

  • Mesothelium


    A single layer of flat squamous epithelial cells

  • Main functions of epithelial tissue?


    1. protection: acts as a physical barrier

    2. absorption: nutrients & substances

    3. secretion: various substances

    4. filtration: helps kidneys with selective passage of substances

    5. sensory reception: detecting external stimuli

  • Areolar Connective Tissue


    Function: wrapping and cushioning organs; macrophages phagocytize bacteria

    Location: In the subcutaneous layer under the skin

    Components: ground substance, elastic fibers, collagen fibers, fibroblastsA

  • Adipose Connective Tissue


    Function: provide reserved food fuel; insulate against heat loss

    Location: in subcutaneous tissue, around kidneys, in eyeballs

    Components: fat droplets, fat cells

  • Reticular Connective Tissue


    Function: forms soft internal skeleton around immune cells

    Location: lymph nodes & spleen

    Components: reticular fibers

  • Dense Regular Connective Tissue


    Function: withstand tension in one direction

    Location: tendons

    Components: fibroblasts, collagen fibers

  • Dense Irregular Connective tissue


    Function: withstand tension in many directions

    Location: dermis of skin

    Components: fibroclasts & collagen fibers

  • Elastic Connective Tissue


    Function: allow tissue to recoil after stretching

    Location: walls of large arteries

    Components: elastic fibers

  • What is the extracellular matrix?


    a mesh structure that surrounds and supports cells

    Components: fibrous proteins, proteoglycans, and glycoproteins

  • Fibroblast


    Function: synthesize and maintain the extracellular matrix

    Ex: collagen & elastin

  • Fibrocyte


    Function: plays role in tissue repair, collagen production, and maintains structural integrity of connective tissue

  • Mast Cell


    Function: monitor for harmful invaders; releases signal to increase blood flow when pathogens are sensed

  • Adipocyte


    Function: specialized fat cells that store energy

  • Reticulocyte


    Function: immature red blood cells that indicate erythropoiesis; can reflect activity of bone marrow

  • What are fibers?


    Thread-like structures that serve to provide support

  • What are the three fiber types?


    1. Collagen Fibers

    2. Elastic Fibers

    3. Reticular Fibers

  • Collagen Fibers


    Composed of collagen

    Function: provide tensile strength

  • Elastic Fibers


    Composed of elastin

    Function: allows stretching and elasticity

  • Reticular Fibers w


    Composed of type 3 collagen

    Function: surround small blood vessels and soft tissue of organs to provide support

  • Hyaline Cartilage


    Function: support and reinforces

    Location: tip of nose

    Components: matrix, lacunae, chondrocytes (in lacunae)

  • Elastic Cartilage


    Function: maintains shape while allowing great flexibility

    Location: epiglottis

    Components: Elastic Fibers, Lacunae, Chondrocyte

  • Fibrocartilage


    Function: tensile strength allows it to absorb compressive shock

    Locations: intervertebral discs

    Components: collagen fibers & chondrocytes in lacunae

  • Osseous Connective Tissue


    Function: supports and protects; provides levers for muscles to act on

    Location: bones ex: femur

    Components: central canal, lamella, lacunae, osteocytes

  • Lacunae


    Small cavities in bone that contain cells responsible for maintenance

  • Chondroblasts


    produce and maintain cartilage by secreting extracellular matrix & differentiating into chondrocytes

  • Chondrocytes


    Produce and maintain the extracellular matrix

  • Osteoblasts


    Bone formation; bone reshaping, healing, skeletal development, metabolic activity

  • Osteocytes


    mature bone cells that play a role in maintaining bone health, regulating mineral balance, and remodeling

  • Osteoclasts


    Responsible for breaking down and reabsorbing old or damaged bone tissue

  • Perichondrium


    Dense connective tissue that envelops cartilage that is not at a joint

  • Which cartilage has the most visible fibers?


    Elastic Cartilage

  • What type of cartilage is the most abundant in the body?


    Hyaline Cartilage

  • Does cartilage heal better than bone?


    No, bone heals better because it is highly vascular