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Ch. 5 The Integumentary System
Hoehn - Marieb Human Anatomy & Physiology, 12th edition
Hoehn, Haynes, Abbott12th EditionMarieb Human Anatomy & PhysiologyISBN: 9780138242732Not the one you use?Change textbook
All textbooksHoehn, Haynes, Abbott 12th EditionCh. 5 The Integumentary SystemProblem 14
Chapter 5, Problem 14

Which epidermal cells contain keratohyaline and lamellar granules?

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Understand that the epidermis is composed of several layers of cells, each with distinct functions and characteristics.
Recall that keratohyaline granules are involved in the process of keratinization, helping to form the dense protein matrix in the skin's outer layer.
Recognize that lamellar granules contain lipids that contribute to the skin's waterproof barrier by filling spaces between cells.
Identify the specific epidermal cell type that contains both keratohyaline and lamellar granules; these are the cells in the stratum granulosum layer.
Conclude that the keratinocytes in the stratum granulosum are the epidermal cells containing keratohyaline and lamellar granules, playing a key role in skin barrier formation.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Epidermal Cell Types

The epidermis consists of several cell types, including keratinocytes, melanocytes, Langerhans cells, and Merkel cells. Keratinocytes are the most abundant and are responsible for producing keratin and other granules essential for skin barrier function.
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Other Epidermal Cells

Keratohyaline Granules

Keratohyaline granules are dense, protein-rich structures found in the granular layer of keratinocytes. They contain profilaggrin, which helps in the aggregation of keratin filaments, contributing to the formation of the skin’s protective outer layer.
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3:08
Granulocytes

Lamellar Granules

Lamellar granules are lipid-containing organelles in keratinocytes that release lipids into the extracellular space. These lipids form a waterproof barrier, preventing water loss and protecting the skin from external environmental damage.
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Guided course
2:52
Structure of Lamellae
Related Practice
Textbook Question

Mrs. Gaucher received second-degree burns on her abdomen when she dropped a kettle of boiling water. She asked her doctor (worriedly) if she would need a skin graft. What do you think he told her?

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Textbook Question

The rule of nines is helpful clinically in

a. Diagnosing skin cancer

b. Estimating the extent of a burn

c. Estimating how serious a cancer is

d. Preventing acne

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Textbook Question

Skin surface markings that reflect points of tight dermal attachment to underlying tissues are called

(a) tension lines,

(b) flexure lines,

(c) papillary ridges,

(d) dermal papillae.

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Textbook Question

Why are there no skin cancers that originate from stratum corneum cells?

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Textbook Question

Explain each of these familiar phenomena in terms of what you learned in this chapter:

a. Pimples

b. Dandruff

c. Greasy hair and 'shiny nose

d. Stretch marks from gaining weight

e. Freckles

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