After a heavy meal rich with fried foods, Debby Collins, an overweight 45-year-old woman, was rushed to the emergency room with severe spasmodic pains in her epigastric region that radiated to the right side of her rib cage. She indicated that the attack came on suddenly, and her abdomen was found to be tender to the touch and somewhat rigid. What do you think is this patient's problem and why is her pain discontinuous (colicky)? What are the treatment options and what might happen if the problem is not resolved?

Troy Francis, a middle-aged salesman, complains of a burning pain in the 'pit of his stomach,' usually beginning about two hours after eating and abating after drinking a glass of milk. When asked to indicate the site, he points to his epigastric region. The GI tract is examined by X-ray fluoroscopy. A gastric ulcer is visualized, and drug therapy using a proton pump inhibitor and antibiotics is recommended.
a. Why is this treatment suggested?
b. What are the possible consequences of nontreatment?
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Key Concepts
Pathophysiology of Gastric Ulcers
Role of Proton Pump Inhibitors and Antibiotics in Treatment
Complications of Untreated Gastric Ulcers
A baby is admitted to the hospital with a history of diarrhea and watery feces occurring over the last three days. The baby has sunken fontanelles (the not yet ossified spaces between skull bones in infants), indicating extreme dehydration. Tests indicate that the baby has a bacterium-induced colitis, and antibiotics are prescribed. Because of the baby's loss of intestinal juices, do you think that his blood pH would indicate acidosis or alkalosis? Explain your reasoning.
Dr. Dolan used an endoscope to view Mr. Habib’s colon. He noted the presence of several polyps and removed them during the same procedure. What is an endoscope? Why did Dr. Dolan opt to remove the polyps immediately?
Mr. Holden has had severe diarrhea all day and is severely weakened. Explain why his nurse is concerned about his present condition.
Explain why activation of pancreatic enzymes is delayed until they reach the small intestine.
