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Ch. 5 The Integumentary System
Marieb - Human Anatomy & Physiology 7th Edition
Marieb, Hoehn7th EditionHuman Anatomy & PhysiologyISBN: 9780805359091Not the one you use?Change textbook
Chapter 5, Problem 2

Which cell functions as part of the immune system?
a. Keratinocyte
b. Melanocyte
c. Dendritic cell
d. Tactile epithelial cell

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1
Step 1: Understand the function of each cell type listed in the options to identify which one is involved in the immune system.
Step 2: Recall that keratinocytes are the primary cells in the epidermis responsible for producing keratin, which provides a protective barrier but is not directly part of the immune response.
Step 3: Recognize that melanocytes produce melanin, the pigment responsible for skin color, and protect against UV radiation, but they do not function in immune defense.
Step 4: Identify dendritic cells as antigen-presenting cells that capture pathogens and activate the immune system, playing a crucial role in immune surveillance and response.
Step 5: Note that tactile epithelial cells (Merkel cells) are involved in sensory reception (touch) and do not participate in immune functions.

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Key Concepts

Here are the essential concepts you must grasp in order to answer the question correctly.

Immune System Cells in the Skin

Certain cells in the skin play active roles in the immune response by detecting pathogens and presenting antigens to other immune cells. These cells help initiate and regulate immune defense mechanisms to protect the body from infections.
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Dendritic Cells

Dendritic cells are specialized antigen-presenting cells found in the skin and other tissues. They capture pathogens, process their antigens, and present them to T cells, thus activating the adaptive immune response.
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The Epidermis: Cells Example 2

Functions of Other Skin Cells

Keratinocytes form the skin barrier and produce keratin, melanocytes produce pigment to protect against UV radiation, and tactile epithelial cells are involved in sensory reception. None of these primarily function in immune defense.
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