Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

1. Introduction to Biochemistry

Entropy

Biochemistry

1. Introduction to Biochemistry

Entropy

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Multiple Choice

Which entropic factor primarily destabilizes helical DNA at high temperature?

Increased disorder of water molecules surrounding DNA

Decreased entropy of the DNA backbone

Decreased entropy of base stacking interactions

Increased conformational entropy of single-stranded DNA

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Verified step by step guidance

Understand the concept of entropy: Entropy is a measure of disorder or randomness in a system. In the context of DNA, conformational entropy refers to the freedom of movement and flexibility of the DNA strands.

Recognize the structural difference between double-stranded and single-stranded DNA: Double-stranded DNA is more ordered due to the base pairing and helical structure, while single-stranded DNA has greater flexibility and randomness, leading to higher conformational entropy.

Analyze the effect of high temperature on DNA: At high temperatures, the hydrogen bonds between complementary bases in double-stranded DNA break, leading to the separation of the strands into single-stranded DNA. This process increases the conformational entropy of the DNA strands.

Eliminate incorrect options: Increased disorder of water molecules surrounding DNA is not the primary factor destabilizing helical DNA at high temperature. Similarly, decreased entropy of the DNA backbone and decreased entropy of base stacking interactions do not explain the destabilization as effectively as increased conformational entropy of single-stranded DNA.

Conclude that the primary entropic factor destabilizing helical DNA at high temperature is the increased conformational entropy of single-stranded DNA, as the strands gain more freedom and flexibility upon separation.