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Multiple Choice
Which of the following best describes the difference between NAD$^+$ and NADH?
A
NAD$^+$ is the oxidized form, while NADH is the reduced form.
B
NAD$^+$ acts as an electron donor, while NADH acts as an electron acceptor.
C
NAD$^+$ is found only in DNA, while NADH is found only in RNA.
D
NAD$^+$ contains two phosphate groups, whereas NADH contains only one.
Verified step by step guidance
1
Step 1: Begin by understanding the role of NAD$^+$ and NADH in biochemical reactions. NAD$^+$ (nicotinamide adenine dinucleotide) is a coenzyme involved in redox reactions, where it alternates between oxidized (NAD$^+$) and reduced (NADH) forms.
Step 2: Clarify the oxidation and reduction states. NAD$^+$ is the oxidized form, meaning it can accept electrons during a reaction. NADH is the reduced form, meaning it has already gained electrons and can donate them in subsequent reactions.
Step 3: Examine the statement about electron donor and acceptor roles. NAD$^+$ acts as an electron acceptor because it gains electrons to become NADH. Conversely, NADH acts as an electron donor because it can transfer electrons to other molecules.
Step 4: Address the incorrect statements. NAD$^+$ and NADH are not exclusive to DNA or RNA; they are coenzymes involved in metabolic pathways. Additionally, both NAD$^+$ and NADH contain two phosphate groups, so the statement about differing phosphate numbers is incorrect.
Step 5: Conclude by identifying the correct description: NAD$^+$ is the oxidized form, while NADH is the reduced form. This distinction is fundamental to understanding their roles in cellular metabolism and energy transfer.