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Multiple Choice
Which of the following functional groups confers acidic properties to amino acids?
A
Hydroxyl group (\(-OH\))
B
Carboxyl group (\(-COOH\))
C
Sulfhydryl group (\(-SH\))
D
Amino group (\(-NH_2\))
Verified step by step guidance
1
Understand the concept of acidic properties: Acidic properties in molecules are typically conferred by functional groups that can donate a proton ( ext{H}^+) to the surrounding environment, lowering the pH.
Examine the carboxyl group ( ext{-COOH}): The carboxyl group contains a hydroxyl group ( ext{-OH}) attached to a carbon atom that is also double-bonded to an oxygen atom. This group can ionize by losing a proton ( ext{H}^+), forming a negatively charged carboxylate ion ( ext{-COO}^-). This ability to donate a proton makes it acidic.
Compare the hydroxyl group ( ext{-OH}): While the hydroxyl group is polar and can form hydrogen bonds, it does not readily donate a proton under physiological conditions, so it does not confer significant acidic properties.
Analyze the sulfhydryl group ( ext{-SH}): The sulfhydryl group is involved in forming disulfide bonds and is not strongly acidic under physiological conditions. It does not readily donate a proton like the carboxyl group.
Evaluate the amino group ( ext{-NH}_2): The amino group is basic rather than acidic. It tends to accept a proton ( ext{H}^+) rather than donate one, which is the opposite of what is required for acidic properties.