Multiple Choice
Which of the following is the monomer unit of a nucleic acid?
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1. Introduction to Biochemistry
Nucleic Acids
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What is the name of the sugar acid produced when D-ribose is oxidized at the aldehyde group?
A
D-Gluconic acid
B
D-Ribulose
C
D-Ribitol
D
D-Ribonic acid
Verified step by step guidance1
Understand the concept of sugar acids: Sugar acids are formed when the aldehyde group or the terminal hydroxyl group of a sugar is oxidized. In this case, the aldehyde group of D-ribose is oxidized.
Recall the structure of D-ribose: D-ribose is a five-carbon aldose sugar with an aldehyde group at the first carbon (C1). Oxidation of this aldehyde group converts it into a carboxylic acid group.
Identify the naming convention for sugar acids: When the aldehyde group of an aldose sugar is oxidized, the resulting compound is named by replacing the '-ose' suffix with '-onic acid'. For D-ribose, this means the product is D-ribonic acid.
Differentiate between the options provided: D-Gluconic acid is derived from D-glucose, D-Ribulose is a ketose sugar, and D-Ribitol is a sugar alcohol. None of these match the description of the oxidized product of D-ribose.
Conclude that the correct answer is D-Ribonic acid, as it is the sugar acid formed by the oxidation of the aldehyde group in D-ribose.
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