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Multiple Choice
Which of the following is a major chemical buffering system in the human body?
A
Chloride buffer system
B
Sulfate buffer system
C
Bicarbonate buffer system
D
Phosphate buffer system
Verified step by step guidance
1
Understand the concept of a chemical buffering system: A buffering system helps maintain pH stability in the body by neutralizing excess acids or bases. This is crucial for physiological processes that depend on a stable pH environment.
Identify the major buffering systems in the human body: The primary buffering systems include the bicarbonate buffer system, phosphate buffer system, and protein buffer systems. These systems work in different compartments of the body, such as blood, intracellular fluid, and extracellular fluid.
Focus on the bicarbonate buffer system: The bicarbonate buffer system is the most important buffering system in the human body for maintaining blood pH. It involves the equilibrium between carbonic acid (H₂CO₃) and bicarbonate ions (HCO₃⁻). The reaction can be represented as:
Compare the bicarbonate buffer system to other options: The chloride and sulfate buffer systems are not major contributors to pH regulation in the human body. The phosphate buffer system is important in intracellular fluid and the kidneys but is less significant than the bicarbonate buffer system in blood pH regulation.
Conclude why the bicarbonate buffer system is the correct answer: The bicarbonate buffer system is the primary mechanism for maintaining blood pH within the narrow range of 7.35–7.45. It is highly effective due to its ability to interact with respiratory and renal systems to regulate carbon dioxide and bicarbonate levels.