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Multiple Choice
Which of the following compounds cannot be formed from fatty acids?
A
Triglycerides
B
Glucose
C
Phospholipids
D
Ketone bodies
Verified step by step guidance
1
Step 1: Begin by understanding the metabolic pathways of fatty acids. Fatty acids are primarily used for energy production, storage, and the synthesis of certain lipid-based molecules. They undergo β-oxidation to produce acetyl-CoA, which enters the citric acid cycle or is used for other biosynthetic processes.
Step 2: Analyze the formation of triglycerides. Fatty acids can combine with glycerol to form triglycerides, which are the main storage form of fats in the body. This process occurs in the liver and adipose tissue.
Step 3: Examine the synthesis of phospholipids. Fatty acids are integral components of phospholipids, which are essential for cell membrane structure. They combine with glycerol, phosphate groups, and other molecules to form phospholipids.
Step 4: Consider the production of ketone bodies. During prolonged fasting or carbohydrate deprivation, fatty acids are converted into ketone bodies (e.g., acetoacetate, β-hydroxybutyrate) in the liver to provide an alternative energy source for tissues like the brain.
Step 5: Evaluate the formation of glucose. Fatty acids cannot be converted into glucose because the conversion of acetyl-CoA (produced from fatty acid oxidation) into glucose is not possible due to the irreversible nature of the pyruvate dehydrogenase reaction. This is a key metabolic limitation in humans.