Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

What does the enzyme's active site do in order to bind more tightly to the substrate?

It increases the temperature of the substrate.

It undergoes a conformational change to better fit the substrate (induced fit model).

It hydrolyzes ATP to provide energy for binding.

It permanently changes its primary amino acid sequence.

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Verified step by step guidance

Understand the role of the enzyme's active site: The active site is the region of the enzyme where the substrate binds and the chemical reaction occurs. It is highly specific to the substrate's shape and chemical properties.

Learn about the induced fit model: The induced fit model explains that the enzyme's active site is flexible and can undergo a conformational change to better accommodate the substrate. This enhances the binding and catalytic efficiency.

Eliminate incorrect options: Analyze the provided choices. Increasing the temperature of the substrate, hydrolyzing ATP for binding, or permanently changing the enzyme's primary amino acid sequence are not mechanisms used by the active site to bind the substrate more tightly.

Focus on the correct mechanism: The conformational change in the active site allows the enzyme to form a more precise fit with the substrate, stabilizing the enzyme-substrate complex and facilitating the reaction.

Relate this concept to enzyme specificity: The induced fit model highlights the dynamic nature of enzyme-substrate interactions, emphasizing that enzymes are not rigid structures but adapt to optimize binding and catalysis.