Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

Biochemistry

6. Enzymes and Enzyme Kinetics

Enzyme-Substrate Complex

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Multiple Choice

How does the three-dimensional shape of an enzyme determine its role within a cell?

It ensures the enzyme can only function outside the cell membrane.

It enables the enzyme to randomly interact with any molecule in the cell.

It allows the enzyme to specifically bind to its substrate, facilitating the correct chemical reaction.

It causes the enzyme to be permanently inactive.

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Verified step by step guidance

Understand the concept of enzyme specificity: Enzymes are proteins that act as biological catalysts, speeding up chemical reactions in the cell. Their three-dimensional shape is crucial for their function because it determines their ability to bind specifically to their substrate.

Learn about the active site: The active site is a region on the enzyme where the substrate binds. The shape and chemical properties of the active site are complementary to the substrate, ensuring specificity. This is often described as a 'lock and key' model.

Explore the role of enzyme-substrate interaction: When the substrate binds to the enzyme's active site, it forms an enzyme-substrate complex. This interaction facilitates the chemical reaction by lowering the activation energy required for the reaction to proceed.

Understand the importance of enzyme structure: The enzyme's three-dimensional structure is maintained by various types of bonds, such as hydrogen bonds, ionic bonds, and disulfide bridges. Any change in this structure (e.g., due to denaturation) can affect the enzyme's ability to bind to its substrate and perform its function.

Recognize the specificity of enzyme function: The enzyme's shape ensures it does not randomly interact with molecules in the cell or function outside the cell membrane. Instead, it specifically binds to its substrate to catalyze the correct chemical reaction, playing a vital role in cellular processes.