Multiple Choice
Which of the following statements about protein primary structure is true?
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4. Protein Structure
Primary Structure of Protein
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Which of the following best describes the primary structure of a protein?
A
The linear sequence of amino acids joined by peptide bonds
B
The local folding of the polypeptide chain into alpha-helices and beta-sheets
C
The association of multiple polypeptide subunits into a functional protein complex
D
The overall three-dimensional shape of a single polypeptide chain
Verified step by step guidance1
Understand the concept of protein structure: Proteins have four levels of structure—primary, secondary, tertiary, and quaternary. Each level describes a different aspect of the protein's organization.
Define the primary structure: The primary structure refers to the linear sequence of amino acids in a polypeptide chain, connected by peptide bonds. This sequence is determined by the genetic code.
Differentiate primary structure from other levels: Secondary structure involves local folding into alpha-helices and beta-sheets, tertiary structure describes the overall 3D shape of a single polypeptide, and quaternary structure refers to the association of multiple polypeptide subunits.
Identify the correct description: Among the options provided, the primary structure is best described as 'The linear sequence of amino acids joined by peptide bonds.'
Review the importance of primary structure: The sequence of amino acids in the primary structure determines the higher levels of protein structure and ultimately the protein's function.
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