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Multiple Choice
In the context of protein secondary structure, is the alpha helix typically a right-handed or left-handed coil?
A
Left-handed
B
Both right-handed and left-handed
C
Neither; it is not helical
D
Right-handed
Verified step by step guidance
1
Understand the concept of protein secondary structure: Protein secondary structure refers to the local folding of the polypeptide chain into regular structures such as alpha helices and beta sheets, stabilized by hydrogen bonds.
Learn about the alpha helix: The alpha helix is a common secondary structure in proteins, characterized by a helical shape where the backbone forms a spiral stabilized by hydrogen bonds between the carbonyl oxygen of one amino acid and the amide hydrogen of another amino acid four residues away.
Determine the handedness of the alpha helix: The handedness of a helix refers to the direction in which the helix spirals. A right-handed helix spirals clockwise when viewed from the top, while a left-handed helix spirals counterclockwise.
Recall the typical handedness of the alpha helix: In naturally occurring proteins, the alpha helix is almost always right-handed due to the stereochemistry of amino acids and the energetically favorable interactions in this configuration.
Conclude that the alpha helix is typically right-handed: Based on the structural and energetic considerations, the alpha helix in proteins is predominantly right-handed.