Table of contents

1. Introduction to Biochemistry4h 34m
2. Water3h 23m
3. Amino Acids8h 10m
4. Protein Structure10h 4m
5. Protein Techniques14h 5m
6. Enzymes and Enzyme Kinetics13h 38m
7. Enzyme Inhibition and Regulation 8h 42m
8. Protein Function 9h 41m
9. Carbohydrates7h 49m
10. Lipids5h 49m
11. Biological Membranes and Transport 6h 37m
12. Biosignaling9h 45m
Review 1: Nucleic Acids, Lipids, & Membranes2h 47m
Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway3h 12m
Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism2h 26m
Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation1h 48m

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

Biochemistry

7. Enzyme Inhibition and Regulation

Enzyme Inhibition

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Multiple Choice

Why are denatured enzymes no longer functional?

Denaturation disrupts the enzyme's three-dimensional structure, preventing substrate binding at the active site.

Denaturation increases the enzyme's affinity for its substrate, making the reaction irreversible.

Denaturation causes the enzyme to become more stable and resistant to inhibitors.

Denaturation results in the enzyme being converted into a cofactor.

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Verified step by step guidance

Understand the concept of enzyme denaturation: Denaturation refers to the process where an enzyme loses its native three-dimensional structure due to external factors such as heat, pH changes, or chemical agents. This structural change disrupts the enzyme's functionality.

Recall the importance of the enzyme's three-dimensional structure: The specific folding of an enzyme creates an active site, which is the region where the substrate binds. This structure is critical for the enzyme's catalytic activity.

Analyze the effect of denaturation on the active site: When an enzyme is denatured, the active site is altered or destroyed. This prevents the substrate from binding properly, thereby halting the enzyme's ability to catalyze reactions.

Eliminate incorrect options: Denaturation does not increase the enzyme's affinity for its substrate, nor does it make the enzyme more stable or convert it into a cofactor. These statements are scientifically inaccurate.

Conclude with the correct explanation: Denaturation disrupts the enzyme's three-dimensional structure, preventing substrate binding at the active site, which is why denatured enzymes are no longer functional.