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Multiple Choice
In considering protein secondary structure, which of the following statements is incorrect?
A
Secondary structure is determined by the sequence of amino acids.
B
Beta sheets can be parallel or antiparallel.
C
Alpha helices are stabilized by hydrogen bonds between the backbone atoms.
D
Hydrogen bonds in secondary structures occur between the carbonyl oxygen and amide hydrogen.
Verified step by step guidance
1
Understand that protein secondary structure refers to the local folded structures that form within a polypeptide due to interactions between atoms in the backbone. The two most common types are alpha helices and beta sheets.
Recognize that the sequence of amino acids primarily determines the primary structure of a protein, not the secondary structure. Secondary structure is influenced by hydrogen bonding patterns.
Identify that beta sheets can indeed be parallel or antiparallel, depending on the direction of the polypeptide chains involved.
Acknowledge that alpha helices are stabilized by hydrogen bonds, which occur between the carbonyl oxygen of one amino acid and the amide hydrogen of another, typically four residues apart.
Conclude that the incorrect statement is that secondary structure is determined by the sequence of amino acids, as it is actually determined by hydrogen bonding patterns between the backbone atoms.