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Multiple Choice
Which class of signaling receptors includes members that are sensitive to hormones such as adrenaline and glucagon?
A
Receptor tyrosine kinases
B
Nuclear hormone receptors
C
Ligand-gated ion channels
D
G protein-coupled receptors (GPCRs)
Verified step by step guidance
1
Step 1: Begin by understanding the concept of signaling receptors. These are specialized proteins that detect and respond to external signals, such as hormones, neurotransmitters, or other molecules, to initiate a cellular response.
Step 2: Review the characteristics of G protein-coupled receptors (GPCRs). GPCRs are a large family of membrane-bound receptors that interact with G proteins to transmit signals inside the cell. They are sensitive to a variety of molecules, including hormones like adrenaline and glucagon.
Step 3: Compare GPCRs with other receptor classes mentioned in the problem: Receptor tyrosine kinases, Nuclear hormone receptors, and Ligand-gated ion channels. Note that GPCRs are unique in their ability to bind hormones like adrenaline and glucagon and activate intracellular signaling pathways via G proteins.
Step 4: Recall that adrenaline and glucagon are examples of hormones that act on GPCRs to regulate processes such as energy metabolism and stress responses. This specificity helps distinguish GPCRs from other receptor types.
Step 5: Conclude that the correct answer is G protein-coupled receptors (GPCRs), as they are the class of signaling receptors sensitive to hormones like adrenaline and glucagon.