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Multiple Choice
Which step in glycolysis involves the reduction of NAD+ to NADH?
A
Hexokinase reaction
B
Pyruvate kinase reaction
C
Glyceraldehyde-3-phosphate dehydrogenase reaction
D
Phosphofructokinase reaction
Verified step by step guidance
1
Understand that glycolysis is a metabolic pathway that converts glucose into pyruvate, releasing energy and reducing equivalents in the form of NADH.
Identify the role of NAD+ in glycolysis. NAD+ is a coenzyme that acts as an electron carrier, accepting electrons during certain reactions to form NADH.
Recognize that the reduction of NAD+ to NADH occurs during the oxidation of glyceraldehyde-3-phosphate. This is a key step in glycolysis where energy is conserved in the form of NADH.
Focus on the enzyme involved: glyceraldehyde-3-phosphate dehydrogenase. This enzyme catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate, coupled with the reduction of NAD+ to NADH.
Note that this step is crucial for the continuation of glycolysis, as it provides the necessary NADH for subsequent energy-yielding processes in cellular respiration.