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Multiple Choice
Which of the following best describes the function of the DNA helicase enzyme in the DNA replication process?
A
It joins Okazaki fragments together on the lagging strand.
B
It removes RNA primers from the newly synthesized DNA.
C
It synthesizes new DNA strands by adding nucleotides to a primer.
D
It unwinds the double-stranded DNA by breaking hydrogen bonds between the bases.
Verified step by step guidance
1
Understand the role of DNA helicase in the DNA replication process. DNA helicase is an enzyme responsible for unwinding the double-stranded DNA by breaking the hydrogen bonds between complementary base pairs (adenine-thymine and guanine-cytosine). This creates single-stranded DNA templates for replication.
Eliminate incorrect options by analyzing their descriptions. For example, joining Okazaki fragments is the function of DNA ligase, not helicase. Removing RNA primers is performed by DNA polymerase I, and synthesizing new DNA strands is the role of DNA polymerase III.
Focus on the correct description of DNA helicase's function. It unwinds the DNA helix, creating a replication fork where the leading and lagging strands are exposed for replication.
Relate the unwinding process to the breaking of hydrogen bonds. DNA helicase uses energy from ATP hydrolysis to break these bonds, separating the strands and allowing replication machinery to access the DNA template.
Conclude that the correct answer is: 'It unwinds the double-stranded DNA by breaking hydrogen bonds between the bases,' as this accurately describes the primary function of DNA helicase during replication.