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Multiple Choice
Which enzyme is responsible for proofreading during DNA replication?
A
Ligase
B
DNA polymerase
C
Helicase
D
Primase
Verified step by step guidance
1
Understand the process of DNA replication: DNA replication is the process by which a cell duplicates its DNA before cell division. It involves several enzymes that each play a specific role.
Identify the role of DNA polymerase: DNA polymerase is the enzyme responsible for synthesizing new DNA strands by adding nucleotides complementary to the template strand.
Learn about proofreading: During DNA replication, errors can occur when incorrect nucleotides are incorporated. Proofreading is a mechanism that corrects these errors to ensure the fidelity of DNA replication.
Recognize the proofreading function of DNA polymerase: DNA polymerase has a proofreading ability through its 3' to 5' exonuclease activity, which allows it to remove incorrectly paired nucleotides and replace them with the correct ones.
Differentiate between the enzymes: Ligase is involved in joining DNA fragments, helicase unwinds the DNA double helix, and primase synthesizes RNA primers. None of these enzymes have a proofreading function during DNA replication.