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Multiple Choice
In which phase of mitosis do the sister chromatids separate at their centromeres?
A
Metaphase
B
Telophase
C
Prophase
D
Anaphase
Verified step by step guidance
1
Understand the process of mitosis, which is the division of a single cell into two genetically identical daughter cells. Mitosis consists of several phases: prophase, metaphase, anaphase, and telophase.
Recall that during metaphase, the chromosomes align at the cell's equatorial plane, and the spindle fibers attach to the centromeres of the sister chromatids.
Recognize that anaphase is the phase where the sister chromatids are pulled apart. The centromeres split, allowing the chromatids to separate and move toward opposite poles of the cell.
Note that telophase is the phase following anaphase, where the separated chromatids reach the poles, and the nuclear envelope begins to reform around each set of chromosomes.
Understand that prophase is the initial phase of mitosis, where the chromatin condenses into visible chromosomes, but the sister chromatids remain attached at the centromere.